• Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-PANK4 antibody (8-58 aa) (STJ193811)

SKU:
STJ193811

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-4 phosphopantetheine phosphatase (8-58 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PANK4
Gene ID: 55229
Uniprot ID: PANK4_HUMAN
Immunogen Region: 8-58 aa
Specificity: This antibody detects endogenous levels of PANK4 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human PANK4 at the amino acid range 8-58
Function Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. May play a role in the physiological regulation of CoA intracellular levels (Probable).
Protein Name 4'-Phosphopantetheine Phosphatase
Inactive Pantothenic Acid Kinase 4
Hpank4
Database Links Reactome: R-HSA-196783
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-4'-Phosphopantetheine Phosphatase antibody
Anti-Inactive Pantothenic Acid Kinase 4 antibody
Anti-Hpank4 antibody
Anti-PANK4 antibody

Information sourced from Uniprot.org

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