| Short Description : | Rabbit polyclonal anti-4 phosphopantetheine phosphatase (8-58 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PANK4 |
| Gene ID: | 55229 |
| Uniprot ID: | PANK4_HUMAN |
| Immunogen: | Synthesized peptide derived from the human PANK4 at the amino acid range 8-58 |
| Immunogen Region: | 8-58 aa |
| Specificity: | This antibody detects endogenous levels of PANK4 at Human/Mouse/Rat |
| Function | Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. May play a role in the physiological regulation of CoA intracellular levels (Probable). |
| Protein Name | 4'-Phosphopantetheine PhosphataseInactive Pantothenic Acid Kinase 4Hpank4 |
| Database Links | Reactome: R-HSA-199220 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-4'-Phosphopantetheine Phosphatase antibodyAnti-Inactive Pantothenic Acid Kinase 4 antibodyAnti-Hpank4 antibodyAnti-PANK4 antibody |
Information sourced from Uniprot.org
