Anti-Pan-KRT2 antibody (151-200 aa) (STJ96694)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human Keratin around the non-acetylation site of Lys185 AND OTHERS at the amino acid range 151-200
General Information
| Short Description | Rabbit polyclonal anti-Pan-Keratin, type II cytoskeletal 2 epidermal (151-200 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRT2 |
| Gene ID | 3849 |
| Uniprot ID | K22E_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human Keratin around the non-acetylation site of Lys185 AND OTHERS at the amino acid range 151-200 |
| Immunogen Region | 151-200 aa |
| Specificity | Keratin-pan Polyclonal Antibody detects endogenous levels of Keratin-pan protein. |
Additional Info
| Function | Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins. Plays a role in the establishment of the epidermal barrier on plantar skin. |
| Protein Name | Keratin - Type Ii Cytoskeletal 2 EpidermalCytokeratin-2eCk-2eEpithelial Keratin-2eKeratin-2 EpidermisKeratin-2eK2eType-Ii Keratin Kb2 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Keratin - Type Ii Cytoskeletal 2 Epidermal antibodyAnti-Cytokeratin-2e antibodyAnti-Ck-2e antibodyAnti-Epithelial Keratin-2e antibodyAnti-Keratin-2 Epidermis antibodyAnti-Keratin-2e antibodyAnti-K2e antibodyAnti-Type-Ii Keratin Kb2 antibodyAnti-KRT2 antibodyAnti-KRT2A antibodyAnti-KRT2E antibody |
Information sourced from Uniprot.org