Anti-Pallidin antibody (50-100 aa) (STJ13100238)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from human Pallidin conjugated to blue carrier protein was used as the antigen. The peptide shares 95% identity with rat and mouse sequences.
General Information
| Short Description | Rabbit polyclonal anti-Pallidin (50-100 aa) for use in IHC and WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:100 to 1:2000 is recommended. The optimal dilution should be determined by the end user. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | BLOC1S6 |
| Gene ID | 26258 |
| Uniprot ID | BL1S6_HUMAN |
| Immunogen | A synthetic peptide from human Pallidin conjugated to blue carrier protein was used as the antigen. The peptide shares 95% identity with rat and mouse sequences. |
| Immunogen Region | 50-100 aa |
| Specificity | Specific for Pallidin. |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process. |
| Protein Name | Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6Bloc-1 Subunit 6Pallid Protein HomologPallidinSyntaxin 13-Interacting Protein |
| Database Links | Reactome: R-HSA-432722 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinIt Can Exist As A Soluble Protein As Well As A Peripheral Membrane Protein |
| Alternative Antibody Names | Anti-Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6 antibodyAnti-Bloc-1 Subunit 6 antibodyAnti-Pallid Protein Homolog antibodyAnti-Pallidin antibodyAnti-Syntaxin 13-Interacting Protein antibodyAnti-BLOC1S6 antibodyAnti-PA antibodyAnti-PLDN antibody |
Information sourced from Uniprot.org