Anti-PAIP2 antibody (STJA0008188)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PAIP2
General Information
| Short Description | Rabbit polyclonal anti-Polyadenylate-binding protein-interacting protein 2-binding protein-interacting protein 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PAIP2 |
| Gene ID | 51247 |
| Uniprot ID | PAIP2_HUMAN |
| Immunogen | Synthesized peptide derived from human PAIP2 |
| Specificity | This antibody detects endogenous levels of PAIP2 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | Ubiquitinated, leading to its degradation by the proteasome. |
| Function | Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization. |
| Protein Name | Polyadenylate-Binding Protein-Interacting Protein 2Pabp-Interacting Protein 2Paip-2Poly(A-Binding Protein-Interacting Protein 2 |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Polyadenylate-Binding Protein-Interacting Protein 2 antibodyAnti-Pabp-Interacting Protein 2 antibodyAnti-Paip-2 antibodyAnti-Poly(A-Binding Protein-Interacting Protein 2 antibodyAnti-PAIP2 antibodyAnti-PAIP2A antibodyAnti-HSPC218 antibody |
Information sourced from Uniprot.org