| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Parkin coregulated gene protein (18-68 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PACRG |
| Gene ID: |
135138 |
| Uniprot ID: |
PACRG_HUMAN |
| Immunogen Region: |
18-68 aa |
| Specificity: |
This antibody detects endogenous levels of PACRG at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human PACRG at the amino acid range 18-68 |
| Function | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease. |
| Protein Name | Parkin Coregulated Gene ProteinMolecular Chaperone/Chaperonin-Binding ProteinPark2 Coregulated Gene Protein |
| Cellular Localisation | CytoplasmCytoskeletonCilium Axoneme |
| Alternative Antibody Names | Anti-Parkin Coregulated Gene Protein antibodyAnti-Molecular Chaperone/Chaperonin-Binding Protein antibodyAnti-Park2 Coregulated Gene Protein antibodyAnti-PACRG antibodyAnti-GLUP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
