Anti-p504s antibody [IHC524] (STJA0042236)

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STJA0042236
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Host: Rabbit
Applications: IHC-p
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-p504s for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : IHC524
Conjugation: Unconjugated
Formulation: Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Storage Instruction: Store at 2-8°C for up to 1 year. Do not freeze.
Specificity: Tested and validated on prostate carcinoma tissue.
Background p504s, also known as Alpha-Methylacyl Coenzyme A Racemase (AMACR) , is an enzyme localized in the peroxisome and mitochondria that functions in Beta-oxidation of branched chain fatty acids, as well as bile synthesis. AMACR has been clinically indicated as a tissue biomarker for prostate cancer and colorectal cancer, as well as high-grade prostatic intraepithelial neoplasia, a precursor lesion of prostate cancer. p504s overexpression has also been detected in a number of other cancers including ovarian, breast, bladder, lung, and renal cell carcinomas, lymphoma, and melanoma.

Information sourced from Uniprot.org

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