Anti-P2Y12 antibody [R02-2E1] (STJA0035309)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human P2Y12
General Information
| Short Description | Rabbit monoclonal anti-P2Y12 for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-2E1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | P2RY12 |
| Gene ID | 64805 |
| Uniprot ID | P2Y12_HUMAN |
| Immunogen | A synthetic peptide of human P2Y12 |
Additional Info
| Tissue Specificity | Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain. |
| Function | Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. |
| Protein Name | P2y Purinoceptor 12P2y12Adp-Glucose ReceptorAdpg-RP2t(AcP2y(AcP2y(CycP2y12 Platelet Adp ReceptorP2y(AdpSp1999 |
| Database Links | Reactome: R-HSA-392170Reactome: R-HSA-417957Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-P2y Purinoceptor 12 antibodyAnti-P2y12 antibodyAnti-Adp-Glucose Receptor antibodyAnti-Adpg-R antibodyAnti-P2t(Ac antibodyAnti-P2y(Ac antibodyAnti-P2y(Cyc antibodyAnti-P2y12 Platelet Adp Receptor antibodyAnti-P2y(Adp antibodyAnti-Sp1999 antibodyAnti-P2RY12 antibodyAnti-HORK3 antibody |
Information sourced from Uniprot.org