Western blot analysis of lysates from mouse brain using P2RY12 rabbit polyclonal antibody (STJ117783) at 1:2000 dilution. Secondary antibody:HRP Goat Anti-rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25  Mu g per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection:ECL Basic Kit. Exposuretime:45s.

Anti-P2RY12 antibody (303-313) (STJ117783)

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STJ117783
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Host: Rabbit
Applications: WB/IF/ICC/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:1000-1:5000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: P2RY12
Gene ID: 64805
Uniprot ID: P2Y12_HUMAN
Immunogen Region: 303-313
Specificity: A synthetic peptide corresponding to a sequence within amino acids 243-342 of human P2RY12 (NP_795345.1).
Immunogen Sequence: AVFFICFVPFHFARIPYTLS QTRDVFDCTAENTLFYVKES TLWLTSLNACLDPFIYFFLC KSFRNSLISMLKCPNSATSL SQDNRKKEQDGGDPNEETPM
Tissue Specificity Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain.
Function Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation.
Protein Name P2y Purinoceptor 12
P2y12
Adp-Glucose Receptor
Adpg-R
P2t(Ac
P2y(Ac
P2y(Cyc
P2y12 Platelet Adp Receptor
P2y(Adp
Sp1999
Database Links Reactome: R-HSA-392170
Reactome: R-HSA-417957
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-P2y Purinoceptor 12 antibody
Anti-P2y12 antibody
Anti-Adp-Glucose Receptor antibody
Anti-Adpg-R antibody
Anti-P2t(Ac antibody
Anti-P2y(Ac antibody
Anti-P2y(Cyc antibody
Anti-P2y12 Platelet Adp Receptor antibody
Anti-P2y(Adp antibody
Anti-Sp1999 antibody
Anti-P2RY12 antibody
Anti-HORK3 antibody

Information sourced from Uniprot.org

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