Anti-P-cadherin antibody (108-654 aa) [SRM5450] (STJ11107364)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal P-cadherin (108-654 aa) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM5450 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1500-1:6000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDH3 |
| Gene ID | 1001 |
| Uniprot ID | CADH3_HUMAN |
| Immunogen Region | 108-654 aa |
| Immunogen Sequence | DWVVAPISVPENGKGPFPQR LNQLKSNKDRDTKIFYSITG PGADSPPEGVFAVEKETGWL LLNKPLDREEIAKYELFGHA VSENGASVEDPMNISIIVTD QNDHKPKFTQDTFRGSVLEG VLPGTSVMQVTATDEDDAIY TYNGVVAYSIHSQEPKDPHD LMFTIHRSTGTISVISSGLD REKVPEYTLTIQATDMDGDG STTTAVAVVEILDANDNAPM FDPQKYEAHVPENAVGHEV |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 108-654 of human P-cadherin (NP_001784.2). |
Additional Info
| Tissue Specificity | Expressed in some normal epithelial tissues and in some carcinoma cell lines. |
| Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells.cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Protein Name | Cadherin-3Placental CadherinP-Cadherin |
| Database Links | Reactome: R-HSA-418990 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Cadherin-3 antibodyAnti-Placental Cadherin antibodyAnti-P-Cadherin antibodyAnti-CDH3 antibodyAnti-CDHP antibody |
Information sourced from Uniprot.org