| Host: |
Rabbit |
| Applications: |
IHC/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Otogelin (2706-2756 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC-P 1:50-200IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
OTOG |
| Gene ID: |
340990 |
| Uniprot ID: |
OTOG_HUMAN |
| Immunogen Region: |
2706-2756 aa |
| Specificity: |
This antibody detects endogenous levels of OTOG at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human OTOG at the amino acid range 2706-2756 |
| Function | Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes. |
| Protein Name | Otogelin |
| Database Links | Reactome: R-HSA-9662361 |
| Cellular Localisation | Apical Cell MembranePeripheral Membrane ProteinExtracellular SideSecretedExtracellular SpaceFound In Fiber-Like Structures During The Maturation Process Of The Tectorial Membrane |
| Alternative Antibody Names | Anti-Otogelin antibodyAnti-OTOG antibodyAnti-OTGN antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
