Anti-OTOG antibody (2706-2756 aa) (STJ196568)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human OTOG at the amino acid range 2706-2756
General Information
| Short Description | Rabbit polyclonal anti-Otogelin (2706-2756 aa) for use in IHC and IF in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-200IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OTOG |
| Gene ID | 340990 |
| Uniprot ID | OTOG_HUMAN |
| Immunogen | Synthesized peptide derived from the human OTOG at the amino acid range 2706-2756 |
| Immunogen Region | 2706-2756 aa |
| Specificity | This antibody detects endogenous levels of OTOG at Human/Mouse |
Additional Info
| Function | Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes. |
| Protein Name | Otogelin |
| Database Links | Reactome: R-HSA-9662361 |
| Cellular Localisation | Apical Cell MembranePeripheral Membrane ProteinExtracellular SideSecretedExtracellular SpaceFound In Fiber-Like Structures During The Maturation Process Of The Tectorial Membrane |
| Alternative Antibody Names | Anti-Otogelin antibodyAnti-OTOG antibodyAnti-OTGN antibody |
Information sourced from Uniprot.org