Anti-OSMR antibody (100-979) (STJ28764)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal OSMR (100-979) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OSMR |
| Gene ID | 9180 |
| Uniprot ID | OSMR_HUMAN |
| Immunogen Region | 100-979 |
| Immunogen Sequence | ESELPLECATHFVRIKSLVD DAKFPEPNFWSNWSSWEEVS VQDSTGQDILFVFPKDKLVE EGTNVTICYVSRNIQNNVSC YLEGKQIHGEQLDPHVTAFN L |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human OSMR (NP_003990.1). |
Additional Info
| Tissue Specificity | Expressed in keratinocytes (at protein level). Expressed at relatively high levels in all neural cells as well as fibroblast and epithelial cells. |
| Function | Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. |
| Protein Name | Oncostatin-M-Specific Receptor Subunit BetaInterleukin-31 Receptor Subunit BetaIl-31 Receptor Subunit BetaIl-31r Subunit BetaIl-31r-BetaIl-31rb |
| Database Links | Reactome: R-HSA-6788467 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Oncostatin-M-Specific Receptor Subunit Beta antibodyAnti-Interleukin-31 Receptor Subunit Beta antibodyAnti-Il-31 Receptor Subunit Beta antibodyAnti-Il-31r Subunit Beta antibodyAnti-Il-31r-Beta antibodyAnti-Il-31rb antibodyAnti-OSMR antibodyAnti-OSMRB antibody |
Information sourced from Uniprot.org