| Short Description : | Mouse monoclonal Oncostatin-M antibody for use in ELISA and FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA/FC |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | SAA0470 |
| Isotype: | IgG2aL |
| Conjugation: | Unconjugated |
| Concentration: | 1.18 mg/ml |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Formulation: | 0.01M PBS, pH 7.4. |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months. |
| Gene Symbol: | OSM |
| Gene ID: | 5008 |
| Uniprot ID: | ONCM_HUMAN |
| Function | Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration. |
| Protein Name | Oncostatin-MOsm |
| Database Links | Reactome: R-HSA-6785807Reactome: R-HSA-6788467 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Oncostatin-M antibodyAnti-Osm antibodyAnti-OSM antibody |
Information sourced from Uniprot.org