Anti-OsIRE1 antibody (436-650 aa) (STJ11103999)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal OsIRE1 (436-650 aa) antibody for use in WB and ELISA in o.sativa samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | O.sativa |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Immunogen Region | 436-650 aa |
| Immunogen Sequence | ARKKDGLINSTQIFSASDKE GNGTGGSTEAQSNKAHDSTN VELPNGLNGRQIGKLCVYSK EIGKGSNGTVVFEGSYGGRE VAVKRLLRSHNDIASKEIEN LIASDQDPNIVRMYGFEQDN DFVYISLERCRCSLADLIQL HSVPPFSNTKGTDIELWRQD GLPSAQLLKLMRDVVAGIVH LHSLGIIHRDLKPQNVLISK EGPLRAKLSDMGISK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 436-650 of Oryza sativa OsIRE1 (Q7XIT1). |
Additional Info
| Background | Involved in endoplasmic reticulum (ER) stress response. Senses unfolded proteins in the lumen of the ER via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices bZIP50 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response (UPR) transcriptional activator, which then induces transcription of UPR target genes, such as luminal-binding protein (BiP) chaperones. |
Information sourced from Uniprot.org