Anti-ORP150 antibody [R04-5C1] (STJA0034666)

SKU:
STJA0034666
$184.23 - $388.47
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Short Description :Rabbit monoclonal anti-ORP150 for use in WB, IHC-F, IHC-P, ICC, IF and IP in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-F/IHC-P/ICC/IF/IP
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R04-5C1
Isotype:IgG
Conjugation:Unconjugated
Concentration:0.3 mg/mL
Purification:Affinity Purified
Dilution Range:WB 1:500-1:1000
IHC 1:50-1:100
IF 1:50-1:200
IP 1:20
Formulation:50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:HYOU1
Gene ID:10525
Uniprot ID:HYOU1_HUMAN
Immunogen:A synthetic peptide of human ORP150
Tissue Specificity Highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers.
Function Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. Promotes HSPA5/BiP-mediated ATP nucleotide exchange and thereby activates the unfolded protein response (UPR) pathway in the presence of endoplasmic reticulum stress. May play a role as a molecular chaperone and participate in protein folding.
Protein Name Hypoxia Up-Regulated Protein 1
150 Kda Oxygen-Regulated Protein
Orp-150
170 Kda Glucose-Regulated Protein
Grp-170
Heat Shock Protein Family H Member 4
Database Links Reactome: R-HSA-3000484
Reactome: R-HSA-381038
Cellular Localisation Endoplasmic Reticulum Lumen
Alternative Antibody Names Anti-Hypoxia Up-Regulated Protein 1 antibody
Anti-150 Kda Oxygen-Regulated Protein antibody
Anti-Orp-150 antibody
Anti-170 Kda Glucose-Regulated Protein antibody
Anti-Grp-170 antibody
Anti-Heat Shock Protein Family H Member 4 antibody
Anti-HYOU1 antibody
Anti-GRP170 antibody
Anti-HSPH4 antibody
Anti-ORP150 antibody

Information sourced from Uniprot.org