Anti-ORC1 antibody (696-856) (STJ116956)

Name: Anti-ORC1 antibody (696-856) (STJ116956)
SKU: STJ116956
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ116956

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Short Description	Rabbit polyclonal ORC1 (696-856) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	ORC1
Gene ID	4998
Uniprot ID	ORC1_HUMAN
Immunogen Region	696-856
Immunogen Sequence	EDDAIQLVARKVAALSGDAR RCLDICRRATEICEFSQQKP DSPGLVTIAHSMEAVDEMFS SSYITAIKNSSVLEQSFLRA ILAEFRRSGLEEATFQQIYS QHVALCRMEGLPYPTMSETM AVCSHLGSCRLLLVEPSRND LLLRVRLNVSQDDVLYALKD E
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 696-856 of human ORC1 (NP_001177748.1).

Post Translational Modifications	Phosphorylated during mitosis.
Function	Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Protein Name	Origin Recognition Complex Subunit 1 Replication Control Protein 1
Database Links	Reactome: R-HSA-113507 Reactome: R-HSA-176187 Reactome: R-HSA-68616 Reactome: R-HSA-68689 Reactome: R-HSA-68867 Reactome: R-HSA-68949 Reactome: R-HSA-68962 Reactome: R-HSA-69205
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Origin Recognition Complex Subunit 1 antibody Anti-Replication Control Protein 1 antibody Anti-ORC1 antibody Anti-ORC1L antibody Anti-PARC1 antibody

Information sourced from Uniprot.org