Anti-ORC1 antibody (696-856) (STJ116956)

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STJ116956
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Applications:WB/ELISA
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:ORC1
Gene ID:4998
Uniprot ID:ORC1_HUMAN
Immunogen Region:696-856
Immunogen Sequence:EDDAIQLVARKVAALSGDAR RCLDICRRATEICEFSQQKP DSPGLVTIAHSMEAVDEMFS SSYITAIKNSSVLEQSFLRA ILAEFRRSGLEEATFQQIYS QHVALCRMEGLPYPTMSETM AVCSHLGSCRLLLVEPSRND LLLRVRLNVSQDDVLYALKD E
Specificity:Recombinant fusion protein containing a sequence corresponding to amino acids 696-856 of human ORC1 (NP_001177748.1).
Post Translational Modifications Phosphorylated during mitosis.
Function Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
Protein Name Origin Recognition Complex Subunit 1
Replication Control Protein 1
Database Links Reactome: R-HSA-113507
Reactome: R-HSA-176187
Reactome: R-HSA-68616
Reactome: R-HSA-68689
Reactome: R-HSA-68867
Reactome: R-HSA-68949
Reactome: R-HSA-68962
Reactome: R-HSA-69205
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Origin Recognition Complex Subunit 1 antibody
Anti-Replication Control Protein 1 antibody
Anti-ORC1 antibody
Anti-ORC1L antibody
Anti-PARC1 antibody

Information sourced from Uniprot.org