![Anti-Oct-3/4 antibody [N1NK] (STJ16101778)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/152284/347132/STJ16101778_1__87567.1681999402.jpg?c=1 "Anti-Oct-3/4 antibody [N1NK] (STJ16101778)")
![Anti-Oct-3/4 antibody [N1NK] (STJ16101778)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/152284/347132/STJ16101778_1__87567.1681999402.jpg?c=1 "Anti-Oct-3/4 antibody [N1NK] (STJ16101778)")
| Short Description : | Mouse monoclonal anti-Oct-3/4 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | N1NK |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Concentration: | >=69 mg/L |
| Dilution Range: | IHC-P 1:100 |
| Formulation: | Tissue culture supernatant with sodium azide |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Immunogen: | Prokaryotic recombinant protein corresponding to 147 amino acids of the N-terminus of the human Oct-3/4 molecule. |
| Background | Oct-3/4 is a member of the POU homeodomain family of transcription factors, which is expressed by embryonic stem cells and germ cells. A critical amount of Oct-3/4 is required to maintain stem cell self replication. Down regulation of Oct-3/4 levels are associated with loss of pluripotency. Oct-3/4 has been proposed as a useful marker for germ cell tumors which exhibit features of pluripotentiality, including seminoma/dysgerminoma/germinoma and embryonal carcinoma, and establishing a germ cell origin for some metastatic tumors of uncertain primary origin. |
Information sourced from Uniprot.org
