Anti-Oct-2 antibody [IHC642] (STJA0042228)

SKU:
STJA0042228
£148.50 - £439.50
Processing The item has been added

Host: Mouse
Applications: IHC-p
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal anti-Oct-2 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : IHC642
Conjugation: Unconjugated
Formulation: Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Storage Instruction: Store at 2-8°C for up to 1 year. Do not freeze.
Gene Symbol: POU2F2
Gene ID: 5452
Uniprot ID: PO2F2_HUMAN
Specificity: Tested and validated on tonsil, lymph node tissue.
Tissue Specificity Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.
Function Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates IL6 expression in B cells with POU2AF1. Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5: Activates the U2 small nuclear RNA (snRNA) promoter.
Protein Name Pou Domain - Class 2 - Transcription Factor 2
Lymphoid-Restricted Immunoglobulin Octamer-Binding Protein Nf-A2
Octamer-Binding Protein 2
Oct-2
Octamer-Binding Transcription Factor 2
Otf-2
Database Links Reactome: R-HSA-6807505
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Pou Domain - Class 2 - Transcription Factor 2 antibody
Anti-Lymphoid-Restricted Immunoglobulin Octamer-Binding Protein Nf-A2 antibody
Anti-Octamer-Binding Protein 2 antibody
Anti-Oct-2 antibody
Anti-Octamer-Binding Transcription Factor 2 antibody
Anti-Otf-2 antibody
Anti-POU2F2 antibody
Anti-OCT2 antibody
Anti-OTF2 antibody

Information sourced from Uniprot.org