Anti-OCIAD1 antibody (1-245) (STJ113235)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal OCIAD1 (1-245) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | OCIAD1 |
| Gene ID | 54940 |
| Uniprot ID | OCAD1_HUMAN |
| Immunogen Region | 1-245 |
| Immunogen Sequence | MNGRADFREPNAEVPRPIPH IGPDYIPTEEERRVFAECND ESFWFRSVPLAATSMLITQG LISKGILSSHPKYGSIPKLI LACIMGYFAGKLSYVKTCQE KFKKLENSPLGEALRSGQAR RSSPPGHYYQKSKYDSSVSG QSSFVTSPAADNIEMLPHYE PIPFSSSMNESAPTGITDHI VQGPDPNLEESPKRKNITYE ELRNKNRESYEVSLTQKTDP SVRPMHERVPKKEVKVNKY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human OCIAD1 (NP_060300.1). |
Additional Info
| Tissue Specificity | Isoform 1 is highly expressed in many tissues, including testis, brain, placenta, ovary, prostate and mammary gland. Isoform 2 expression is restricted to the central nervous system including brain, cerebellum and spinal cord. |
| Function | Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes. Involved in integrin-mediated cancer cell adhesion and colony formation in ovarian cancer. |
| Protein Name | Ocia Domain-Containing Protein 1Ovarian Cancer Immunoreactive Antigen Domain Containing 1Ovarian Carcinoma Immunoreactive Antigen |
| Database Links | |
| Cellular Localisation | Endosome |
| Alternative Antibody Names | Anti-Ocia Domain-Containing Protein 1 antibodyAnti-Ovarian Cancer Immunoreactive Antigen Domain Containing 1 antibodyAnti-Ovarian Carcinoma Immunoreactive Antigen antibodyAnti-OCIAD1 antibodyAnti-ASRIJ antibodyAnti-OCIA antibody |
Information sourced from Uniprot.org