| Host: | Rabbit |
| Applications: | ELISA/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Occludin (450-523) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Biotin |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.5-1.5 µg/µl |
| Dilution Range: | WB: 1:2, 500-1:5, 000ELISA: 1:50, 000IP: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | Ocln |
| Gene ID: | 83497 |
| Uniprot ID: | OCLN_RAT |
| Immunogen Region: | 450-523 |
| Immunogen: | Synthetic peptide taken within amino acid region 450-523 on rat Occludin protein. |
| Post Translational Modifications | Dephosphorylated by PTPRJ. |
| Function | May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. May be involved in the organization of actin in endothelial cells. |
| Protein Name | Occludin |
| Database Links | Reactome: R-RNO-351906 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell JunctionTight Junction |
| Alternative Antibody Names | Anti-Occludin antibodyAnti-Ocln antibody |
Information sourced from Uniprot.org