| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | OASL |
| Gene ID: | 8638 |
| Uniprot ID: | OASL_HUMAN |
| Immunogen Region: | 1-350 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human OASL (NP_003724.1). |
| Immunogen Sequence: | MALMQELYSTPASRLDSFVA QWLQPHREWKEEVLDAVRTV EEFLRQEHFQGKRGLDQDVR VLKVVKVGSFGNGTVLRSTR EVELVAFLSCFHSFQEAAKH HKDVLRLIWKTMWQSQDLLD LGLEDLRMEQRVPDALVFTI QTRGTAEPITVTIVPAYRAL GPSLPNSQPPPEVYVSLIKA CGGPGNFCPSFSELQRNFVK HRPTKLKSLLRLVKHWYQQY VKARSPRANLPPLYALELL |
| Function | Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L. |
| Protein Name | 2'-5'-Oligoadenylate Synthase-Like Protein2'-5'-Oas-Related Protein2'-5'-Oas-Rp59 Kda 2'-5'-Oligoadenylate Synthase-Like ProteinThyroid Receptor-Interacting Protein 14Tr-Interacting Protein 14Trip-14P59 OaslP59oasl |
| Database Links | Reactome: R-HSA-877300Reactome: R-HSA-8983711Reactome: R-HSA-909733 |
| Cellular Localisation | Isoform P56: NucleusNucleolusCytoplasmIsoform P30: Cytoplasm |
| Alternative Antibody Names | Anti-2'-5'-Oligoadenylate Synthase-Like Protein antibodyAnti-2'-5'-Oas-Related Protein antibodyAnti-2'-5'-Oas-Rp antibodyAnti-59 Kda 2'-5'-Oligoadenylate Synthase-Like Protein antibodyAnti-Thyroid Receptor-Interacting Protein 14 antibodyAnti-Tr-Interacting Protein 14 antibodyAnti-Trip-14 antibodyAnti-P59 Oasl antibodyAnti-P59oasl antibodyAnti-OASL antibodyAnti-TRIP14 antibody |
Information sourced from Uniprot.org