Anti-NVL antibody (320-400 aa) (STJ96412)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from NVL at the amino acid range 320-400
STJ96412
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General Information

Short DescriptionRabbit polyclonal anti-Nuclear valosin-containing protein-like (320-400 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-1:2000
ELISA 1:20000
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolNVL
Gene ID4931
Uniprot IDNVL_HUMAN
ImmunogenSynthesized peptide derived from NVL at the amino acid range 320-400
Immunogen Region320-400 aa
SpecificityNVL Polyclonal Antibody detects endogenous levels of NVL protein.

Additional Info

Function Participates in the assembly of the telomerase holoenzyme and effecting of telomerase activity via its interaction with TERT. Involved in both early and late stages of the pre-rRNA processing pathways. Spatiotemporally regulates 60S ribosomal subunit biogenesis in the nucleolus. Catalyzes the release of specific assembly factors, such as WDR74, from pre-60S ribosomal particles through the ATPase activity.
Protein Name Nuclear Valosin-Containing Protein-Like
Nvlp
Nuclear Vcp-Like Protein
Database Links
Cellular Localisation Isoform 2: Nucleus
Nucleoplasm
Isoform 1: Nucleus
Nucleolus
Nucleus
Expressed Predominantly In The Nucleolus
Associates With Pre-Ribosomal Particles In The Nucleus
Alternative Antibody Names Anti-Nuclear Valosin-Containing Protein-Like antibody
Anti-Nvlp antibody
Anti-Nuclear Vcp-Like Protein antibody
Anti-NVL antibody
Anti-NVL2 antibody

Information sourced from Uniprot.org

Citations

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