Function | Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates. Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters. Exhibits decapping activity towards dpCoA-capped RNAs in vitro. |
Protein Name | Acyl-Coenzyme A Diphosphatase Nudt19Nucleoside Diphosphate-Linked Moiety X Motif 19Nudix Motif 19 |
Database Links | Reactome: R-HSA-390918Reactome: R-HSA-9033241 |
Cellular Localisation | Peroxisome |
Alternative Antibody Names | Anti-Acyl-Coenzyme A Diphosphatase Nudt19 antibodyAnti-Nucleoside Diphosphate-Linked Moiety X Motif 19 antibodyAnti-Nudix Motif 19 antibodyAnti-NUDT19 antibody |
Information sourced from Uniprot.org