| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Nucleobindin-1 (54-104 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NUCB1 |
| Gene ID: | 4924 |
| Uniprot ID: | NUCB1_HUMAN |
| Immunogen Region: | 54-104 aa |
| Specificity: | This antibody detects endogenous levels of NUCB1 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human NUCB1 at the amino acid range 54-104 |
| Post Translational Modifications | O-glycosylated. |
| Function | Major calcium-binding protein of the Golgi which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates alpha subunits of guanine nucleotide-binding proteins (G proteins). |
| Protein Name | Nucleobindin-1 Calnuc |
| Database Links | Reactome: R-HSA-381426 Reactome: R-HSA-8957275 |
| Cellular Localisation | Golgi Apparatus Cis-Golgi Network Membrane Peripheral Membrane Protein Lumenal Side Cytoplasm Secreted A Small Fraction Of The Protein May Be Cytoplasmic |
| Alternative Antibody Names | Anti-Nucleobindin-1 antibody Anti-Calnuc antibody Anti-NUCB1 antibody Anti-NUC antibody |
Information sourced from Uniprot.org