Anti-NUBP1 antibody (201-320) (STJ118831)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NUBP1 (201-320) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NUBP1 |
| Gene ID | 4682 |
| Uniprot ID | NUBP1_HUMAN |
| Immunogen Region | 201-320 |
| Immunogen Sequence | PQEVSLQDVRKEINFCRKVK LPIIGVVENMSGFICPKCKK ESQIFPPTTGGAELMCQDLE VPLLGRVPLDPLIGKNCDKG QSFFIDAPDSPATLAYRSII QRIQEFCNLHQSKEENLISS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 201-320 of human NUBP1 (NP_002475.2). |
Additional Info
| Function | Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure. |
| Protein Name | Cytosolic Fe-S Cluster Assembly Factor Nubp1Nucleotide-Binding Protein 1Nbp 1 |
| Database Links | Reactome: R-HSA-2564830 |
| Cellular Localisation | CytoplasmNucleusCell ProjectionCytoskeletonCilium AxonemeCilium Basal BodyMicrotubule Organizing CenterCentrosomeCentrioleEnriched In Centrioles Of Microtubule Asters During ProphasePrometaphase And Telophase Stages Of MitosisLocalized At Centrioles And In The Nucleus At InterphaseColocalizes With Nubp-2 At PrometaphaseSpecifically Localizes To The Axenome Of Motile Cilia As Opposed To Primary Non-Motile CiliaLocalization Is Independent Of Nubp2 And Kifc1 |
| Alternative Antibody Names | Anti-Cytosolic Fe-S Cluster Assembly Factor Nubp1 antibodyAnti-Nucleotide-Binding Protein 1 antibodyAnti-Nbp 1 antibodyAnti-NUBP1 antibodyAnti-NBP antibodyAnti-NBP1 antibody |
Information sourced from Uniprot.org