Anti-NTS antibody (24-148) (STJ114208)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NTS (24-148) antibody for use in WB, IF, ICC and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NTS |
| Gene ID | 4922 |
| Uniprot ID | NEUT_HUMAN |
| Immunogen Region | 24-148 |
| Immunogen Sequence | SDSEEEMKALEADFLTNMHT SKISKAHVPSWKMTLLNVCS LVNNLNSPAEETGEVHEEEL VARRKLPTALDGFSLEAMLT IYQLHKICHSRAFQHWELIQ EDILDTGNDKNGKEEVIKRK IPYIL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 24-148 of human NTS (NP_006174.1). |
Additional Info
| Post Translational Modifications | Neurotensin: Neurotensin is cleaved and degraded by Angiotensin-converting enzyme (ACE) and neprilysin (MME). |
| Function | Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle. |
| Protein Name | Neurotensin/Neuromedin N Cleaved Into - Large Neuromedin NNmn-125 - Neuromedin NNnNmn - NeurotensinNt - Tail Peptide |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | SecretedCytoplasmic VesicleSecretory VesiclePackaged Within Secretory Vesicles |
| Alternative Antibody Names | Anti-Neurotensin/Neuromedin N Cleaved Into - Large Neuromedin N antibodyAnti-Nmn-125 - Neuromedin N antibodyAnti-Nn antibodyAnti-Nmn - Neurotensin antibodyAnti-Nt - Tail Peptide antibodyAnti-NTS antibody |
Information sourced from Uniprot.org