| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NTS |
| Gene ID: | 4922 |
| Uniprot ID: | NEUT_HUMAN |
| Immunogen Region: | 24-148 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-148 of human NTS (NP_006174.1). |
| Immunogen Sequence: | SDSEEEMKALEADFLTNMHT SKISKAHVPSWKMTLLNVCS LVNNLNSPAEETGEVHEEEL VARRKLPTALDGFSLEAMLT IYQLHKICHSRAFQHWELIQ EDILDTGNDKNGKEEVIKRK IPYIL |
| Post Translational Modifications | Neurotensin: Neurotensin is cleaved and degraded by Angiotensin-converting enzyme (ACE) and neprilysin (MME). |
| Function | Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle. |
| Protein Name | Neurotensin/Neuromedin N Cleaved Into - Large Neuromedin NNmn-125 - Neuromedin NNnNmn - NeurotensinNt - Tail Peptide |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
| Cellular Localisation | SecretedCytoplasmic VesicleSecretory VesiclePackaged Within Secretory Vesicles |
| Alternative Antibody Names | Anti-Neurotensin/Neuromedin N Cleaved Into - Large Neuromedin N antibodyAnti-Nmn-125 - Neuromedin N antibodyAnti-Nn antibodyAnti-Nmn - Neurotensin antibodyAnti-Nt - Tail Peptide antibodyAnti-NTS antibody |
Information sourced from Uniprot.org