Anti-NTRK3/TrkC antibody [SAA1967] (STJA0020395)

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STJA0020395
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Host: Mouse
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Nt-3 Growth Factor Receptor is suitable for use in ELISA research applications.
Clonality : Monoclonal
Clone ID : SAA1967
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: 0.01M PBS
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: NTRK3
Gene ID: 4916
Uniprot ID: NTRK3_HUMAN
Post Translational Modifications Ligand-mediated auto-phosphorylation.
Function Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
Protein Name Nt-3 Growth Factor Receptor
Gp145-Trkc
Trk-C
Neurotrophic Tyrosine Kinase Receptor Type 3
Trkc Tyrosine Kinase
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-2219530
Reactome: R-HSA-388844
Reactome: R-HSA-6811558
Reactome: R-HSA-9034013
Reactome: R-HSA-9034015
Reactome: R-HSA-9034793
Reactome: R-HSA-9034864
Reactome: R-HSA-9603381
Reactome: R-HSA-9603505
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Nt-3 Growth Factor Receptor antibody
Anti-Gp145-Trkc antibody
Anti-Trk-C antibody
Anti-Neurotrophic Tyrosine Kinase Receptor Type 3 antibody
Anti-Trkc Tyrosine Kinase antibody
Anti-NTRK3 antibody
Anti-TRKC antibody

Information sourced from Uniprot.org