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Anti-NTRK3 antibody (32-429 aa) [4G5] (STJ98432)

Western blot analysis using Trk C monoclonal antibody against extracellular domain of human Trk C (aa32-429).

Anti-NTRK3 antibody (32-429 aa) [4G5] (STJ98432)

SKU:

STJ98432

£144.00 - £348.00

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Mouse
Applications:	WB/ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-NT-3 growth factor receptor (32-429 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Monoclonal
Clone ID:	4G5
Conjugation:	Unconjugated
Isotype:	IgG1
Formulation:	Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 ELISA 1:10000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	NTRK3
Gene ID:	4916
Uniprot ID:	NTRK3_HUMAN
Immunogen Region:	32-429 aa
Specificity:	Trk C Monoclonal Antibody detects endogenous levels of Trk C protein.
Immunogen:	Purified recombinant extracellular fragment of human Trk C (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.

Post Translational Modifications	Ligand-mediated auto-phosphorylation.
Function	Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
Protein Name	Nt-3 Growth Factor Receptor Gp145-Trkc Trk-C Neurotrophic Tyrosine Kinase Receptor Type 3 Trkc Tyrosine Kinase
Database Links	Reactome: R-HSA-1257604 Reactome: R-HSA-2219530 Reactome: R-HSA-388844 Reactome: R-HSA-6811558 Reactome: R-HSA-9034013 Reactome: R-HSA-9034015 Reactome: R-HSA-9034793 Reactome: R-HSA-9034864 Reactome: R-HSA-9603381 Reactome: R-HSA-9603505
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Nt-3 Growth Factor Receptor antibody Anti-Gp145-Trkc antibody Anti-Trk-C antibody Anti-Neurotrophic Tyrosine Kinase Receptor Type 3 antibody Anti-Trkc Tyrosine Kinase antibody Anti-NTRK3 antibody Anti-TRKC antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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