| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NT5E |
| Gene ID: | 4907 |
| Uniprot ID: | 5NTD_HUMAN |
| Immunogen Region: | 32-264 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 32-264 of human CD73/NT5E (NP_002517.1). |
| Immunogen Sequence: | LHTNDVHSRLEQTSEDSSKC VNASRCMGGVARLFTKVQQI RRAEPNVLLLDAGDQYQGTI WFTVYKGAEVAHFMNALRYD AMALGNHEFDNGVEGLIEPL LKEAKFPILSANIKAKGPLA SQISGLYLPYKVLPVGDEVV GIVGYTSKETPFLSNPGTNL VFEDEITALQPEVDKLKTLN VNKIIALGHSGFEMDKLIAQ KVRGVDVVVGGHSNTFLYTG NPPSKEVPAGKYP |
| Function | Catalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate. Shows a preference for ribonucleotide monophosphates over their equivalent deoxyribose forms. Other substrates include IMP, UMP, GMP, CMP, dAMP, dCMP, dTMP, NAD and NMN. |
| Protein Name | 5'-Nucleotidase 5'-Nt 5'-Deoxynucleotidase Ecto-5'-Nucleotidase Imp-Specific 5'-Nucleotidase Thymidylate 5'-Phosphatase Cd Antigen Cd73 |
| Database Links | Reactome: R-HSA-196807 Reactome: R-HSA-73621 Reactome: R-HSA-74259 Reactome: R-HSA-9660826 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor |
| Alternative Antibody Names | Anti-5'-Nucleotidase antibody Anti-5'-Nt antibody Anti-5'-Deoxynucleotidase antibody Anti-Ecto-5'-Nucleotidase antibody Anti-Imp-Specific 5'-Nucleotidase antibody Anti-Thymidylate 5'-Phosphatase antibody Anti-Cd Antigen Cd73 antibody Anti-NT5E antibody Anti-NT5 antibody Anti-NTE antibody |
Information sourced from Uniprot.org