| Short Description : | Rabbit polyclonal anti-Protein FAN (147-197 aa) for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NSMAF |
| Gene ID: | 8439 |
| Uniprot ID: | FAN_HUMAN |
| Immunogen: | Synthesized peptide derived from the human FAN at the amino acid range 147-197 |
| Immunogen Region: | 147-197 aa |
| Specificity: | This antibody detects endogenous levels of FAN at Human/Mouse |
| Function | Couples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE). Specifically binds to the N-smase activation domain of TNF-R55. May regulate ceramide production by N-SMASE. |
| Protein Name | Protein FanFactor Associated With Neutral Sphingomyelinase ActivationFactor Associated With N-Smase Activation |
| Database Links | Reactome: R-HSA-5626978 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Protein Fan antibodyAnti-Factor Associated With Neutral Sphingomyelinase Activation antibodyAnti-Factor Associated With N-Smase Activation antibodyAnti-NSMAF antibodyAnti-FAN antibody |
Information sourced from Uniprot.org
