Anti-NSE antibody [9601] (STJ400142)

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STJ400142
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Short Description :Mouse monoclonal anti-NSE for use in CLIA and FIA in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:CLIA/FIA
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :9601
Isotype:IgG1
Conjugation:Unconjugated
Concentration:5.0 mg/ml (+/-10 %)
Formulation:50 mM citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative
Storage Instruction:Store at 2–8 °C, and do not freeze.
Immunogen:Group D as described in Paus et al. (2011)
Specificity:Antibody recognizes human neuron-specific enolase, gamma isoform. Recognizes NNE (non-neuronal enolase)
Tissue Specificity The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
Function Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.
Protein Name Gamma-Enolase
2-Phospho-D-Glycerate Hydro-Lyase
Enolase 2
Neural Enolase
Neuron-Specific Enolase
Nse
Database Links Reactome: R-HSA-70171
Reactome: R-HSA-70263
Cellular Localisation Cytoplasm
Cell Membrane
Can Translocate To The Plasma Membrane In Either The Homodimeric (Alpha/Alpha) Or Heterodimeric (Alpha/Gamma) Form
Alternative Antibody Names Anti-Gamma-Enolase antibody
Anti-2-Phospho-D-Glycerate Hydro-Lyase antibody
Anti-Enolase 2 antibody
Anti-Neural Enolase antibody
Anti-Neuron-Specific Enolase antibody
Anti-Nse antibody
Anti-ENO2 antibody

Information sourced from Uniprot.org

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