Anti-NSDHL antibody (50-150) [S4204RM] (STJ11104204)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Sterol-4-Alpha-Carboxylate 3-Dehydrogenase-Decarboxylating (50-150) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S4204RM |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NSDHL |
| Gene ID | 50814 |
| Uniprot ID | NSDHL_HUMAN |
| Immunogen Region | 50-150 |
| Immunogen Sequence | GQHMVEQLLARGYAVNVFDI QQGFDNPQVRFFLGDLCSRQ DLYPALKGVNTVFHCASPPP SSNNKELFYRVNYIGTKNVI ETCKEAGVQKLILTSSASVI F |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 50-150 of human NSDHL (NP_057006.1). |
Additional Info
| Tissue Specificity | Brain, heart, liver, lung, kidney, skin and placenta. |
| Function | Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis. Also plays a role in the regulation of the endocytic trafficking of EGFR. |
| Protein Name | Sterol-4-Alpha-Carboxylate 3-Dehydrogenase - DecarboxylatingProtein H105e3 |
| Database Links | Reactome: R-HSA-191273 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Membrane ProteinLipid DropletTrafficking Through The Golgi Is Necessary For Er Membrane Localization |
| Alternative Antibody Names | Anti-Sterol-4-Alpha-Carboxylate 3-Dehydrogenase - Decarboxylating antibodyAnti-Protein H105e3 antibodyAnti-NSDHL antibodyAnti-H105E3 antibody |
Information sourced from Uniprot.org