| Host: |
Rabbit |
| Applications: |
WB/ELISA/IHC |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Neurexin-3-beta (30-110) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-p 1:50-300ELISA 2000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NRXN3 |
| Gene ID: |
9369 |
| Uniprot ID: |
NRX3B_HUMAN |
| Immunogen Region: |
30-110 |
| Specificity: |
Neurexin III Beta Polyclonal Antibody detects endogenous levels of Neurexin III Beta protein. |
| Immunogen: |
Synthesized peptide derived from Neurexin III Beta. at AA range: 30-110 |
| Tissue Specificity | Expressed in the blood vessel walls (at protein level). |
| Post Translational Modifications | Proccessed by alpha-secretase leading to the formation of an extracellular soluble protein as well as a C-terminal membrane-embedded fragment (CTF). Proteolysis of these CTFs by gamma-secretase releases intracellular domains (ICDs) and extracellular peptides. O-glycosylated.contains heparan sulfate. Heparan sulfate attachment is required for synapse development by mediating interactions with neuroligins. |
| Function | Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling. |
| Protein Name | Neurexin-3-BetaNeurexin Iii-Beta Cleaved Into - Neurexin-3-Beta - Soluble Form - Neurexin-3-Beta - C-Terminal FragmentNrxn3-Ctf |
| Database Links | Reactome: R-HSA-6794361 |
| Cellular Localisation | Presynaptic Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Neurexin-3-Beta antibodyAnti-Neurexin Iii-Beta Cleaved Into - Neurexin-3-Beta - Soluble Form - Neurexin-3-Beta - C-Terminal Fragment antibodyAnti-Nrxn3-Ctf antibodyAnti-NRXN3 antibodyAnti-KIAA0743 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
