Anti-NRBP1 antibody (STJ191995)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Nuclear receptor-binding protein for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NRBP1 |
| Gene ID | 29959 |
| Uniprot ID | NRBP_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | NRBP Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Required for embryonic development. Plays a role in intestinal epithelial cell fate and proliferation, thereby involved in the architectural development of the intestine potentially via the regulation of Wnt-responsive genes. May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication. |
| Protein Name | Nuclear Receptor-Binding Protein |
| Database Links | Reactome: R-HSA-383280 |
| Cellular Localisation | CytoplasmCell CortexEndomembrane SystemCell ProjectionLamellipodiumColocalizes With Activated Rac3 To Endomembranes And At The Cell Periphery In Lamellipodia |
| Alternative Antibody Names | Anti-Nuclear Receptor-Binding Protein antibodyAnti-NRBP1 antibodyAnti-BCON3 antibodyAnti-NRBP antibody |
Information sourced from Uniprot.org