| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Nuclear receptor-binding protein is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NRBP1 |
| Gene ID: | 29959 |
| Uniprot ID: | NRBP_HUMAN |
| Specificity: | NRBP Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from part of the human protein |
| Function | Required for embryonic development. Plays a role in intestinal epithelial cell fate and proliferation, thereby involved in the architectural development of the intestine potentially via the regulation of Wnt-responsive genes. May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication. |
| Protein Name | Nuclear Receptor-Binding Protein |
| Database Links | Reactome: R-HSA-383280 |
| Cellular Localisation | CytoplasmCell CortexEndomembrane SystemCell ProjectionLamellipodiumColocalizes With Activated Rac3 To Endomembranes And At The Cell Periphery In Lamellipodia |
| Alternative Antibody Names | Anti-Nuclear Receptor-Binding Protein antibodyAnti-NRBP1 antibodyAnti-BCON3 antibodyAnti-NRBP antibody |
Information sourced from Uniprot.org