| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Nuclear receptor subfamily 4 group A member 2 (100-180 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NR4A2 |
| Gene ID: | 4929 |
| Uniprot ID: | NR4A2_HUMAN |
| Immunogen Region: | 100-180 aa |
| Specificity: | NR4A2 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 100-180 |
| Function | Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. |
| Protein Name | Nuclear Receptor Subfamily 4 Group A Member 2 Immediate-Early Response Protein Not Orphan Nuclear Receptor Nurr1 Transcriptionally-Inducible Nuclear Receptor |
| Database Links | Reactome: R-HSA-383280 Reactome: R-HSA-4090294 |
| Cellular Localisation | Cytoplasm Nucleus Mostly Nuclear Oxidative Stress Promotes Cytoplasmic Localization |
| Alternative Antibody Names | Anti-Nuclear Receptor Subfamily 4 Group A Member 2 antibody Anti-Immediate-Early Response Protein Not antibody Anti-Orphan Nuclear Receptor Nurr1 antibody Anti-Transcriptionally-Inducible Nuclear Receptor antibody Anti-NR4A2 antibody Anti-NOT antibody Anti-NURR1 antibody Anti-TINUR antibody |
Information sourced from Uniprot.org