• Western blot analysis of lysates from HeLa, HUVEC, and 293 cells, using NR2F6 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunofluorescence analysis of HepG2 cells, using NR2F6 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using NR2F6 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using EAR2 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-NR2F6 antibody (11-60 aa) (STJ92815)

SKU:
STJ92815

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Nuclear receptor subfamily 2 group F member 6 (11-60 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NR2F6
Gene ID: 2063
Uniprot ID: NR2F6_HUMAN
Immunogen Region: 11-60 aa
Specificity: EAR2 Polyclonal Antibody detects endogenous levels of EAR2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human NR2F6 at the amino acid range 11-60
Function Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock.is required early in the development of the locus coeruleus (LC).
Protein Name Nuclear Receptor Subfamily 2 Group F Member 6
V-Erba-Related Protein 2
Ear-2
Database Links Reactome: R-HSA-383280
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Nuclear Receptor Subfamily 2 Group F Member 6 antibody
Anti-V-Erba-Related Protein 2 antibody
Anti-Ear-2 antibody
Anti-NR2F6 antibody
Anti-EAR2 antibody
Anti-ERBAL2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance