| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-NPY4R (10-100 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | NPY4R |
| Gene ID: | 100996758/5540 |
| Uniprot ID: | NPY4R_HUMAN |
| Immunogen Region: | 10-100 aa |
| Specificity: | Specific for NPY4R. |
| Immunogen: | A synthetic peptide from aa region of 10-100 of human NPY4R conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | G protein-coupled receptor for PPY/pancreatic polypeptide/PP, NPY/neuropeptide Y and PYY/peptide YY that is negatively coupled to cAMP. The rank order of affinity for these polypeptides and their derivatives is PP, PP (2-36) and Ile-31, Gln-34 PP > Pro-34 PYY > PYY and Leu-31, Pro-34 NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13-36) > PP (31-36) > NPY free acid. |
| Protein Name | Neuropeptide Y Receptor Type 4Npy4-RPancreatic Polypeptide Receptor 1Pp1 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Neuropeptide Y Receptor Type 4 antibodyAnti-Npy4-R antibodyAnti-Pancreatic Polypeptide Receptor 1 antibodyAnti-Pp1 antibodyAnti-NPY4R antibodyAnti-PPYR1 antibody |
Information sourced from Uniprot.org