| Short Description : | Goat polyclonal Neuropeptide Y receptor Y2 (355aa C-Term) antibody for use in WB in human, rat, mouse, canine and monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Goat |
| Reactivity: | Human/Rat/Mouse/Canine/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 3 mg/mL |
| Purification: | This antibody is epitope-affinity purified from goat antiserum. |
| Dilution Range: | WB 1:500-1:2000 |
| Formulation: | PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Storage Instruction: | For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours. |
| Gene Symbol: | NPY2R |
| Gene ID: | 4887 |
| Uniprot ID: | NPY2R_HUMAN |
| Accession Number: | ENSG00000185149 |
| Immunogen: | Peptide derived from within residues 355 aa to the C-terminus of human NPY2R protein. |
| Immunogen Region: | 355aa C-Term |
| Immunogen Sequence: | CFKAKKNLEVRKNSGPNDSF FKAKKNLEVRKNSGPNDSFT |
| Specificity: | Detects endogenous levels of NPY2R by Western blot. |
| Tissue Specificity | High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra. |
| Function | Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > Ile-31, Gln-34 PP > Leu-31, Pro-34 NPY > PP, Pro-34 PYY and NPY free acid. |
| Protein Name | Neuropeptide Y Receptor Type 2Npy2-RNpy-Y2 ReceptorY2 Receptor |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Neuropeptide Y Receptor Type 2 antibodyAnti-Npy2-R antibodyAnti-Npy-Y2 Receptor antibodyAnti-Y2 Receptor antibodyAnti-NPY2R antibody |
Information sourced from Uniprot.org
