| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NPY |
| Gene ID: | 4852 |
| Uniprot ID: | NPY_HUMAN |
| Immunogen Region: | 29-97 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 29-97 of NPY (NP_000896.1). |
| Immunogen Sequence: | YPSKPDNPGEDAPAEDMARY YSALRHYINLITRQRYGKRS SPETLISDLLMRESTENVPR TRLEDPAMW |
| Tissue Specificity | One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla. |
| Post Translational Modifications | The neuropeptide Y form is cleaved at Pro-30 by the prolyl endopeptidase FAP (seprase) activity (in vitro). |
| Function | NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. |
| Protein Name | Pro-Neuropeptide Y Cleaved Into - Neuropeptide YNeuropeptide TyrosineNpy - C-Flanking Peptide Of NpyCpon |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594Reactome: R-HSA-9615017 |
| Cellular Localisation | SecretedCytoplasmic VesicleSecretory VesicleNeuronal Dense Core Vesicle |
| Alternative Antibody Names | Anti-Pro-Neuropeptide Y Cleaved Into - Neuropeptide Y antibodyAnti-Neuropeptide Tyrosine antibodyAnti-Npy - C-Flanking Peptide Of Npy antibodyAnti-Cpon antibodyAnti-NPY antibody |
Information sourced from Uniprot.org