| Host: | Goat |
| Applications: | IHC/WB |
| Reactivity: | Human/Mouse/Rat/Rabbit/Xenopus |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-NPY (20-70 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC (cryo and paraffin sections) , WB. A dilution of 1: 300 to 1: 3000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | NPY |
| Gene ID: | 4852 |
| Uniprot ID: | NPY_HUMAN |
| Immunogen Region: | 20-70 aa |
| Specificity: | Specific for NPY. |
| Immunogen: | A synthetic peptide from aa region 20-70 of mouse NPY (Neuropeptide Y) conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in many other species including human, rat, zebrafish and xenopus. |
| Post Translational Modifications | The neuropeptide Y form is cleaved at Pro-30 by the prolyl endopeptidase FAP (seprase) activity (in vitro). |
| Function | NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. |
| Protein Name | Pro-Neuropeptide Y Cleaved Into - Neuropeptide YNeuropeptide TyrosineNpy - C-Flanking Peptide Of NpyCpon |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-418594Reactome: R-HSA-9615017 |
| Cellular Localisation | SecretedCytoplasmic VesicleSecretory VesicleNeuronal Dense Core Vesicle |
| Alternative Antibody Names | Anti-Pro-Neuropeptide Y Cleaved Into - Neuropeptide Y antibodyAnti-Neuropeptide Tyrosine antibodyAnti-Npy - C-Flanking Peptide Of Npy antibodyAnti-Cpon antibodyAnti-NPY antibody |
Information sourced from Uniprot.org
