| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NPM3 |
| Gene ID: | 10360 |
| Uniprot ID: | NPM3_HUMAN |
| Immunogen Region: | 30-140 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-140 of human NPM3 (NP_008924.1). |
| Immunogen Sequence: | APVTMDSFFFGCELSGHTRS FTFKVEEEDDAEHVLALTML CLTEGAKDECNVVEVVARNH DHQEIAVPVANLKLSCQPML SLDDFQLQPPVTFRLKSGSG PVRITGRHQIV |
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Phosphorylated. |
| Function | Plays a role in the regulation of diverse cellular processes such as ribosome biogenesis, chromatin remodeling or protein chaperoning. Modulates the histone chaperone function and the RNA-binding activity of nucleolar phosphoprotein B23/NPM. Efficiently mediates chromatin remodeling when included in a pentamer containing NPM3 and NPM. |
| Protein Name | Nucleoplasmin-3 |
| Cellular Localisation | NucleusNucleolusMainly Found In The Granular Component Of The Nucleolus |
| Alternative Antibody Names | Anti-Nucleoplasmin-3 antibodyAnti-NPM3 antibody |
Information sourced from Uniprot.org