| Short Description : | Rabbit polyclonal anti-NADPH oxidase 3 (287-336) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NOX3 |
| Gene ID: | 50508 |
| Uniprot ID: | NOX3_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NOX3. AA range:287-336 |
| Immunogen Region: | 287-336 |
| Specificity: | Nox3 Polyclonal Antibody detects endogenous levels of Nox3 protein. |
| Post Translational Modifications | N-glycosylated in a CYBA/p22phox-dependent manner. |
| Function | NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor, upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. |
| Protein Name | Nadph Oxidase 3Mitogenic Oxidase 2Mox-2Gp91phox Homolog 3Gp91-3 |
| Database Links | Reactome: R-HSA-5668599Reactome: R-HSA-9013149Reactome: R-HSA-9013423 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Nadph Oxidase 3 antibodyAnti-Mitogenic Oxidase 2 antibodyAnti-Mox-2 antibodyAnti-Gp91phox Homolog 3 antibodyAnti-Gp91-3 antibodyAnti-NOX3 antibodyAnti-MOX2 antibody |
Information sourced from Uniprot.org
