Anti-NOX1 antibody (436-485) (STJ94185)

SKU:
STJ94185
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-NADPH oxidase 1 (436-485) for use in WB and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC
Host:Rabbit
Reactivity:Human/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
IHC-p 1:50-300
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:NOX1
Gene ID:27035
Uniprot ID:NOX1_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from human NOX1. AA range:436-485
Immunogen Region:436-485
Specificity:Mox1 Polyclonal Antibody detects endogenous levels of Mox1 protein.
Tissue Specificity Isoform NOH-1L: Detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes.
Post Translational Modifications Phosphorylation at Thr-430 mediated by PKC/PRKBC positively regulates its interaction with NOXA1 and enzyme activity.
Function NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor. Isoform NOH-1L: NADPH oxidase that catalyzes the generation of superoxide from molecular oxygen utilizing NADPH as an electron donor.
Protein Name Nadph Oxidase 1
Nox-1
Mitogenic Oxidase 1
Mox-1
Nadh/Nadph Mitogenic Oxidase Subunit P65-Mox
Noh-1
Database Links Reactome: R-HSA-5668599
Reactome: R-HSA-9013149
Reactome: R-HSA-9013423
Reactome: R-HSA-9673324
Cellular Localisation Cell Projection
Invadopodium Membrane
Multi-Pass Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Nadph Oxidase 1 antibody
Anti-Nox-1 antibody
Anti-Mitogenic Oxidase 1 antibody
Anti-Mox-1 antibody
Anti-Nadh/Nadph Mitogenic Oxidase Subunit P65-Mox antibody
Anti-Noh-1 antibody
Anti-NOX1 antibody
Anti-MOX1 antibody
Anti-NOH1 antibody

Information sourced from Uniprot.org