| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:2000IHC-P:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NOMO1 |
| Gene ID: | 23420 |
| Uniprot ID: | NOMO1_HUMAN |
| Immunogen Region: | 700-1000 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 700-1000 of human NOMO1 (NP_055102.3). |
| Immunogen Sequence: | KSVQELRREQQLAEIEARRQ EREKNGNEEGEERMTKPPVQ EMVDELQGPFSYDFSYWARS GEKITVTPSSKELLFYPPSM EAVVSGESCPGKLIEIHGKA GLFLEGQIHPELEGVEIVIS EKGASSPLITVFTDDKGAYS VGPLHSDLEYTVTSQKEGYV LTAVEGTIGDFKAYALAGVS FEIKAEDDQPLPGVLLSLSG GLFRSNLLTQDNGILTFSNL SPGQYYFKPMMKEFRFEPS |
| Tissue Specificity | Expressed in colon tumor tissue and in adjacent normal colonic mucosa. |
| Function | Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions. |
| Protein Name | Bos Complex Subunit Nomo1Nodal Modulator 1Pm5 Protein |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Bos Complex Subunit Nomo1 antibodyAnti-Nodal Modulator 1 antibodyAnti-Pm5 Protein antibodyAnti-NOMO1 antibodyAnti-PM5 antibody |
Information sourced from Uniprot.org