• Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using NMU Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HepG2 cells, using NMU Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Neuromedin-U Polyclonal Antibody diluted at 1：500

Anti-NMU antibody (125-174) (STJ94433)

SKU:
STJ94433

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Neuromedin-U (125-174) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NMU
Gene ID: 10874
Uniprot ID: NMU_HUMAN
Immunogen Region: 125-174
Specificity: Neuromedin-U Polyclonal Antibody detects endogenous levels of Neuromedin-U protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human NMU. AA range:125-174
Tissue Specificity Expressed throughout the enteric nervous system with highest levels being found in the jejunum.
Function Neuromedin-U-25: Ligand for receptors NMUR1 and NMUR2. Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder. Neuromedin precursor-related peptide 33: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release although its potency is much lower than that of neuromedin precursor-related peptide 36. Neuromedin precursor-related peptide 36: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release from lactotroph cells in the pituitary gland, probably via the hypothalamic dopaminergic system.
Protein Name Neuromedin-U Cleaved Into - Neuromedin Precursor-Related Peptide 36
Nurp36 - Neuromedin Precursor-Related Peptide 33
Nurp33 - Neuromedin-U-25
Nmu-25
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Reactome: R-HSA-418594
Cellular Localisation Secreted
Alternative Antibody Names Anti-Neuromedin-U Cleaved Into - Neuromedin Precursor-Related Peptide 36 antibody
Anti-Nurp36 - Neuromedin Precursor-Related Peptide 33 antibody
Anti-Nurp33 - Neuromedin-U-25 antibody
Anti-Nmu-25 antibody
Anti-NMU antibody

Information sourced from Uniprot.org

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