Anti-NMRK2 antibody (STJA0004807)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide of human NMRK2
General Information
| Short Description | Rabbit polyclonal anti-Nicotinamide Riboside Kinase 2 for use in IHC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1.56 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:40-1:150 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | NMRK2 |
| Gene ID | 27231 |
| Uniprot ID | NRK2_HUMAN |
| Immunogen | Synthetic peptide of human NMRK2 |
Additional Info
| Tissue Specificity | Predominantly expressed in skeletal muscle and, at a much lower level, in the heart (at protein level). No expression in brain, kidney, liver, lung, pancreas nor placenta. |
| Function | Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis. |
| Protein Name | Nicotinamide Riboside Kinase 2Nrk 2Nmr-K 2Integrin Beta-1-Binding Protein 3Muscle Integrin-Binding ProteinMibpNicotinic Acid Riboside Kinase 2Ribosylnicotinamide Kinase 2Rnk 2Ribosylnicotinic Acid Kinase 2 |
| Database Links | Reactome: R-HSA-196807 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Nicotinamide Riboside Kinase 2 antibodyAnti-Nrk 2 antibodyAnti-Nmr-K 2 antibodyAnti-Integrin Beta-1-Binding Protein 3 antibodyAnti-Muscle Integrin-Binding Protein antibodyAnti-Mibp antibodyAnti-Nicotinic Acid Riboside Kinase 2 antibodyAnti-Ribosylnicotinamide Kinase 2 antibodyAnti-Rnk 2 antibodyAnti-Ribosylnicotinic Acid Kinase 2 antibodyAnti-NMRK2 antibodyAnti-ITGB1BP3 antibodyAnti-NRK2 antibody |
Information sourced from Uniprot.org