| Tissue Specificity | Predominantly expressed in skeletal muscle and, at a much lower level, in the heart (at protein level). No expression in brain, kidney, liver, lung, pancreas nor placenta. |
| Function | Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis. |
| Protein Name | Nicotinamide Riboside Kinase 2Nrk 2Nmr-K 2Integrin Beta-1-Binding Protein 3Muscle Integrin-Binding ProteinMibpNicotinic Acid Riboside Kinase 2Ribosylnicotinamide Kinase 2Rnk 2Ribosylnicotinic Acid Kinase 2 |
| Database Links | Reactome: R-HSA-196807 |
| Alternative Antibody Names | Anti-Nicotinamide Riboside Kinase 2 antibodyAnti-Nrk 2 antibodyAnti-Nmr-K 2 antibodyAnti-Integrin Beta-1-Binding Protein 3 antibodyAnti-Muscle Integrin-Binding Protein antibodyAnti-Mibp antibodyAnti-Nicotinic Acid Riboside Kinase 2 antibodyAnti-Ribosylnicotinamide Kinase 2 antibodyAnti-Rnk 2 antibodyAnti-Ribosylnicotinic Acid Kinase 2 antibodyAnti-NMRK2 antibodyAnti-ITGB1BP3 antibodyAnti-NRK2 antibody |
Information sourced from Uniprot.org
