| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Thioredoxin domain-containing protein 3 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NME8 |
| Gene ID: | 51314 |
| Uniprot ID: | TXND3_HUMAN |
| Specificity: | This antibody detects endogenous levels of TXNDC3 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human TXNDC3 |
| Function | Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. In vitro, it has neither nucleoside diphosphate kinase (NDPK) activity nor reducing activity on disulfide bonds. Exhibits a 3'-5' exonuclease activity with a preference for single-stranded DNA, suggesting roles in DNA proofreading and repair. |
| Protein Name | Thioredoxin Domain-Containing Protein 33'-5' Exonuclease Nme8Nm23-H8Nme/Nm23 Family Member 8Spermatid-Specific Thioredoxin-2Sptrx-2 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Thioredoxin Domain-Containing Protein 3 antibodyAnti-3'-5' Exonuclease Nme8 antibodyAnti-Nm23-H8 antibodyAnti-Nme/Nm23 Family Member 8 antibodyAnti-Spermatid-Specific Thioredoxin-2 antibodyAnti-Sptrx-2 antibodyAnti-NME8 antibodyAnti-SPTRX2 antibodyAnti-TXNDC3 antibody |
Information sourced from Uniprot.org