Anti-NKX6-1 antibody (180-260) (STJ94508)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from Nkx-6.1. at AA range: 180-260
General Information
| Short Description | Rabbit polyclonal anti-Homeobox protein Nkx-6.1 (180-260) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NKX6-1 |
| Gene ID | 4825 |
| Uniprot ID | NKX61_HUMAN |
| Immunogen | Synthesized peptide derived from Nkx-6.1. at AA range: 180-260 |
| Immunogen Region | 180-260 |
| Specificity | Nkx-6.1 Polyclonal Antibody detects endogenous levels of Nkx-6.1 protein. |
Additional Info
| Tissue Specificity | Pancreatic beta cells. |
| Function | Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals. |
| Protein Name | Homeobox Protein Nkx-6.1Homeobox Protein Nk-6 Homolog A |
| Database Links | Reactome: R-HSA-210745Reactome: R-HSA-210747Reactome: R-HSA-9925561 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Homeobox Protein Nkx-6.1 antibodyAnti-Homeobox Protein Nk-6 Homolog A antibodyAnti-NKX6-1 antibodyAnti-NKX6A antibody |
Information sourced from Uniprot.org